SCHEMBL25997262

SCHEMBL25997262

CC1CN(c2ccc3cc(-c4nc5ccccc5s4)c(=O)oc3c2)C1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.62
PIK3CB P42338 1/20 0.62
ALK Q9UM73 2/20 0.56
APP P05067 1/20 0.43
SMN1; SMN2 Q16637 7/20 0.40
KMT2A Q03164 7/20 0.40
NPC1 O15118 6/20 0.40
RAB9A P51151 6/20 0.40
NPSR1 Q6W5P4 2/20 0.40
PKM P14618 1/20 0.40
ALDH1A1 P00352 8/20 0.40
GLA P06280 7/20 0.40
KDM4E B2RXH2 7/20 0.40
HPGD P15428 6/20 0.40
MAPT P10636 6/20 0.40
GAA P10253 4/20 0.40
LMNA P02545 3/20 0.40
MEN1 O00255 6/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
USP2 O75604 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25997260 0.92 PIK3CD (0.58) PIK3CDPIK3CBALKAPPSMN1; SMN2
SCHEMBL15069276 0.91 PIK3CD (0.59) PIK3CDPIK3CBALKAPPSMN1; SMN2
SCHEMBL25997259 0.90 PIK3CD (0.60) PIK3CDPIK3CBALKAPPSMN1; SMN2
SCHEMBL22372346 0.88 PIK3CD (0.62) PIK3CDPIK3CBALKAPPSMN1; SMN2
SCHEMBL4505982 0.86 PIK3CD (0.62) PIK3CDPIK3CBALKAPPSMN1; SMN2
SCHEMBL16674768 0.85 PIK3CD (0.64) PIK3CDPIK3CBALKAPPSMN1; SMN2
SCHEMBL20445755 0.85 PIK3CD (0.54) PIK3CDPIK3CBALKAPPSMN1; SMN2
SCHEMBL4505188 0.84 PIK3CD (0.63) PIK3CDPIK3CBALKAPPSMN1; SMN2
SCHEMBL25997264 0.84 ALK (0.57) PIK3CDPIK3CBALKSMN1; SMN2KMT2A
Hydrochloric Acid SCHEMBL15069133 0.84 PIK3CD (0.62) PIK3CDPIK3CBALKAPPSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12031178-B2 Cyclooctatetraene containing dyes and compositions ILLUMINA CAMBRIDGE LIMITED (GB) 2024-07-09 US disclosed
US-20230265503-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2023-08-24 US disclosed
US-20230265502-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2023-08-24 US disclosed