SCHEMBL2600133

SCHEMBL2600133

CC[C@H]1O[C@@H](c2ccc(Cl)c(Cc3ccc(C#N)nn3)c2)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1C

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2600131 0.90 SLC5A2 (0.58) SLC5A2
SCHEMBL2600134 0.90 SLC5A2 (0.53) SLC5A2
SCHEMBL2600128 0.89 SLC5A2 (0.51) SLC5A2
SCHEMBL2600139 0.87 SLC5A2 (0.49) SLC5A2
SCHEMBL2132088 0.87 SLC5A2 (0.47) SLC5A2
SCHEMBL2600132 0.87 SLC5A2 (0.56) SLC5A2
SCHEMBL2600135 0.86 SLC5A2 (0.55) SLC5A2
SCHEMBL2600122 0.82 SLC5A2 (0.41) SLC5A2
SCHEMBL2600123 0.82 SLC5A2 (0.41) SLC5A2
SCHEMBL2600129 0.80 SLC5A2 (0.47) SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541380-B2 C-aryl glucoside SGLT2 inhibitors and pharmaceutical compositions comprising same GREEN CROSS CORPORATION (KR) 2013-09-24 — — US disclosed
US-20120101051-A1 NOVEL C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME GREEN CROSS CORPORATION (KR) 2012-04-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120101051-A1 NOVEL C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME SLC5A2, SLC5A1, SLC2A2 SLC5A2 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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