SCHEMBL2600144

SCHEMBL2600144

CC[C@H]1O[C@@H](c2ccc(Cl)c(CC(=N)NN)c2)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1C

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 20/20 0.40
▸ SLC5A1 P13866 4/20 0.34
▸ ADRA2A P08913 1/20 0.33
▸ SLC5A11 Q8WWX8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2600127 0.89 SLC5A2 (0.40) SLC5A2SLC5A1
SCHEMBL2600143 0.89 SLC5A2 (0.42) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL2600121 0.86 SLC5A2 (0.42) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL2600124 0.85 SLC5A2 (0.41) SLC5A2SLC5A1
SCHEMBL2600120 0.85 SLC5A2 (0.44) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL15627071 0.85 SLC5A2 (0.44) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL2130587 0.85 BCHE (0.37) SLC5A2
SCHEMBL15627069 0.83 SLC5A2 (0.42) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL14850074 0.83 SLC5A2 (0.42) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL2600150 0.81 SLC5A2 (0.38) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541380-B2 C-aryl glucoside SGLT2 inhibitors and pharmaceutical compositions comprising same GREEN CROSS CORPORATION (KR) 2013-09-24 — — US disclosed
US-20120101051-A1 NOVEL C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME GREEN CROSS CORPORATION (KR) 2012-04-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120101051-A1 NOVEL C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME SLC5A2, SLC5A1, SLC2A2 SLC5A2 1/4885SLC5A1 2/4885ADRA2A 1563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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