Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20320892 | 1.00 | MDM2 (0.44) | MDM2CCKBRHDAC1HDAC6IDO1 | |
| SCHEMBL20320928 | 1.00 | MDM2 (0.44) | MDM2CCKBRHDAC1HDAC6IDO1 | |
| SCHEMBL26346004 | 1.00 | MDM2 (0.44) | MDM2CCKBRHDAC1HDAC6IDO1 | |
| SCHEMBL20320826 | 1.00 | MDM2 (0.44) | MDM2CCKBRHDAC1HDAC6IDO1 | |
| SCHEMBL20305589 | 1.00 | MDM2 (0.44) | MDM2CCKBRHDAC1HDAC6IDO1 | |
| SCHEMBL20320869 | 1.00 | MDM2 (0.44) | MDM2CCKBRHDAC1HDAC6IDO1 | |
| SCHEMBL26011675 | 0.94 | MDM2 (0.46) | MDM2CCKBRHDAC1HDAC6PYGL | |
| SCHEMBL20321233 | 0.94 | MDM2 (0.44) | MDM2CCKBRHDAC1HDAC6PYGL | |
| SCHEMBL26006958 | 0.94 | MDM2 (0.44) | MDM2CCKBRHDAC1HDAC6PYGL | |
| SCHEMBL20320748 | 0.93 | MDM2 (0.43) | MDM2CCKBRHDAC1HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3557998-B1 | COMPOUNS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS INC (US) | 2023-08-16 | — | — | EP | disclosed |