Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.67 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | CDK7 | P50613 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21356981 | 0.86 | MAOB (0.62) | S1PR1S1PR5HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL7352515 | 0.82 | S1PR1 (0.53) | S1PR1S1PR5HRH3PRKD3CDK7 | |
| SCHEMBL3044904 | 0.80 | S1PR1 (1.00) | S1PR1S1PR5PRKD3CDK7JAK3 | |
| SCHEMBL7818112 | 0.78 | S1PR1 (0.47) | S1PR1S1PR5HRH3MEN1KMT2A | |
| SCHEMBL15275222 | 0.78 | MAOB (0.56) | S1PR1S1PR5NPC1RAB9AMEN1 | |
| SCHEMBL12158512 | 0.78 | S1PR1 (0.59) | S1PR1S1PR5NPC1RAB9AMEN1 | |
| SCHEMBL9764604 | 0.78 | HRH3 (0.58) | HRH3LTA4HNPC1RAB9AKDM4E | |
| SCHEMBL24372036 | 0.77 | MAOB (0.56) | S1PR1S1PR5NPC1RAB9AMEN1 | |
| SCHEMBL695873 | 0.77 | S1PR1 (0.57) | S1PR1S1PR5LTA4HNPC1RAB9A | |
| SCHEMBL696249 | 0.77 | S1PR1 (0.54) | S1PR1S1PR5NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3762364-B1 | PYRROLIDINEAMIDE DERIVATIVES AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-08-23 | — | — | EP | disclosed |