Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 15/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26010086 | 0.98 | ADORA1 (0.65) | ADORA1ADORA2ASLC6A3ADORA3ADORA2B | |
| SCHEMBL26010009 | 0.92 | ADORA1 (0.61) | ADORA1ADORA2ASLC6A3ADORA3ADORA2B | |
| SCHEMBL26013106 | 0.90 | ADORA1 (0.59) | ADORA1ADORA2ASLC6A3ADORA3ADORA2B | |
| SCHEMBL26015783 | 0.89 | ADORA1 (0.55) | ADORA1ADORA2ASLC6A3ADORA3ADORA2B | |
| SCHEMBL26012678 | 0.88 | ADORA1 (0.56) | ADORA1ADORA2AADORA3ADORA2BALDH1A1 | |
| SCHEMBL26009694 | 0.88 | ADORA1 (0.56) | ADORA1ADORA2AADORA3ADORA2BALDH1A1 | |
| SCHEMBL26012904 | 0.88 | ADORA1 (0.65) | ADORA1ADORA2ASLC6A3ADORA2BALDH1A1 | |
| SCHEMBL26015695 | 0.88 | ADORA1 (0.55) | ADORA1ADORA2ASLC6A3ADORA3ADORA2B | |
| SCHEMBL25362387 | 0.87 | ADORA1 (0.56) | ADORA1ADORA2AADORA3ADORA2BALDH1A1 | |
| SCHEMBL30511872 | 0.87 | ADORA1 (0.56) | ADORA1ADORA2AADORA3ADORA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158725-A1 | ADENOSINE LIGANDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | LUCY THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |