Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 17/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26011053 | 1.00 | ADORA1 (0.71) | ADORA1ADORA2AADORA3ADORA2BRET | |
| SCHEMBL30511863 | 0.93 | ADORA1 (0.72) | ADORA1ADORA2AADORA3ADORA2BRET | |
| SCHEMBL25362073 | 0.93 | ADORA1 (0.72) | ADORA1ADORA2AADORA3ADORA2BRET | |
| SCHEMBL26017143 | 0.86 | ADORA1 (0.71) | ADORA1ADORA2AADORA3ADORA2BRET | |
| SCHEMBL26017146 | 0.86 | ADORA1 (0.71) | ADORA1ADORA2AADORA3ADORA2BRET | |
| SCHEMBL25362702 | 0.86 | ADORA1 (0.71) | ADORA1ADORA2AADORA3ADORA2BRET | |
| SCHEMBL30511854 | 0.86 | ADORA1 (0.71) | ADORA1ADORA2AADORA3ADORA2BRET | |
| SCHEMBL923752 | 0.85 | ADORA1 (0.70) | ADORA1ADORA2AADORA3ADORA2BHTR1B | |
| SCHEMBL923751 | 0.85 | ADORA1 (0.70) | ADORA1ADORA2AADORA3ADORA2BHTR1B | |
| SCHEMBL12943384 | 0.83 | ADORA1 (0.73) | ADORA1ADORA2AADORA3ADORA2BHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158725-A1 | ADENOSINE LIGANDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | LUCY THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |