Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.39 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605611 | 0.90 | MAPT (0.42) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL14015606 | 0.85 | KMT2A (0.40) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL2601631 | 0.85 | KMT2A (0.40) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL12219484 | 0.80 | MAPT (0.36) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL15241560 | 0.80 | MEN1 (0.39) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL12752722 | 0.76 | MAPT (0.41) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL10544901 | 0.76 | NPSR1 (0.42) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL10544905 | 0.76 | NPSR1 (0.42) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL1476623 | 0.75 | KMT2A (0.40) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL1476620 | 0.75 | KMT2A (0.40) | MAPTMEN1KMT2ANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158798-B2 | Coupling process for preparing quinolone intermediates | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2012-04-17 | — | — | US | disclosed |
| US-20090111991-A1 | Coupling Process For Preparing Quinolone Intermediates | ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (IE) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111991-A1 | Coupling Process For Preparing Quinolone Intermediates | CYP3A4, CYP4B1, CYP4X1 | MAPT 4271/4885MEN1 1363/4885KMT2A 2928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.