Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.70 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21786275 | 0.98 | KRAS (0.69) | KRASSOS1 | |
| SCHEMBL26019261 | 0.87 | KRAS (0.66) | KRASSOS1 | |
| SCHEMBL23074830 | 0.87 | KRAS (0.92) | KRASSOS1 | |
| SCHEMBL23074885 | 0.87 | KRAS (0.92) | KRASSOS1 | |
| SCHEMBL23074835 | 0.87 | KRAS (0.92) | KRASSOS1 | |
| SCHEMBL23282263 | 0.85 | KRAS (0.81) | KRAS | |
| SCHEMBL23282275 | 0.85 | KRAS (0.81) | KRAS | |
| SCHEMBL19637319 | 0.85 | KRAS (0.69) | KRAS | |
| SCHEMBL28793543 | 0.84 | KRAS (0.79) | KRAS | |
| SCHEMBL23074934 | 0.84 | KRAS (0.62) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3844151-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-08-23 | — | — | EP | disclosed |