Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784146 | 0.79 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3CYP1A1CYP1A2 | |
| SCHEMBL14432054 | 0.79 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3CYP1A1CYP1A2 | |
| SCHEMBL8802483 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3CYP1A1CYP1A2 | |
| SCHEMBL14367734 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3CYP1A1CYP1A2 | |
| SCHEMBL25782996 | 0.75 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP1A1CYP1A2 | |
| SCHEMBL22852013 | 0.75 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9844580 | 0.75 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9844582 | 0.75 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL22532128 | 0.74 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3CYP1A1CYP1A2 | |
| SCHEMBL8802436 | 0.72 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116861-A1 | ANTI-DLL3 ANTIBODY AND PHARMACEUTICAL USE THEREOF, AND ANTIBODY-DRUG CONJUGATE CONTAINING ANTI-DLL3 ANTIBODY | 江苏恒瑞医药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |