Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 9/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26028087 | 0.93 | TOP1 (0.61) | TOP1HDAC3HDAC1HDAC6KDM4E | |
| SCHEMBL27317699 | 0.92 | TOP1 (0.60) | TOP1HDAC3HDAC1HDAC6KDM4E | |
| SCHEMBL27189797 | 0.91 | TOP1 (0.60) | TOP1HDAC3HDAC1HDAC6KDM4E | |
| SCHEMBL30531945 | 0.91 | TOP1 (0.60) | TOP1HDAC3HDAC1HDAC6KDM4E | |
| SCHEMBL22304941 | 0.90 | TOP1 (0.58) | TOP1HDAC3HDAC1HDAC6KDM4E | |
| SCHEMBL22893059 | 0.89 | TOP1 (0.63) | TOP1HDAC3HDAC1HDAC6KDM4E | |
| SCHEMBL21297667 | 0.87 | TOP1 (0.61) | TOP1HDAC3HDAC1HDAC6KDM4E | |
| SCHEMBL21297730 | 0.87 | TOP1 (0.61) | TOP1HDAC3HDAC1HDAC6KDM4E | |
| SCHEMBL22893063 | 0.87 | TOP1 (0.56) | TOP1HDAC3HDAC1HDAC6KDM4E | |
| Belotecan SCHEMBL18983 | 0.87 | TOP1 (0.79) | TOP1HDAC3HDAC1HDAC6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4230205-A1 | ANTITUMOR PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Jenkem Technology Co. Ltd. (Tianjin) (CN) | 2023-08-23 | — | — | EP | disclosed |