⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294038 | 0.84 | — | — | |
| SCHEMBL13980120 | 0.84 | — | — | |
| SCHEMBL11947591 | 0.78 | — | — | |
| SCHEMBL24617802 | 0.75 | — | — | |
| SCHEMBL8313618 | 0.73 | — | — | |
| SCHEMBL12534616 | 0.73 | — | — | |
| SCHEMBL14214223 | 0.73 | — | — | |
| SCHEMBL24097043 | 0.69 | MCL1 (0.50) | — | |
| SCHEMBL21755857 | 0.68 | — | — | |
| SCHEMBL12534612 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234545-A2 | HYDRAZIDE CONTAINING NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | Karyopharm Therapeutics Inc. (US) | 2023-08-30 | — | — | EP | disclosed |