Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308711 | 0.89 | CYP1A2 (0.50) | HRH3CYP1A2CYP2A6CYP17A1CYP3A4 | |
| SCHEMBL18308712 | 0.88 | ESR1 (0.41) | HRH3CYP1A2CYP2A6CYP17A1CYP3A4 | |
| SCHEMBL18308707 | 0.84 | CYP1A2 (0.59) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL26031789 | 0.82 | ESR1 (0.52) | CYP1A2CYP2A6CYP17A1TSHRNPC1 | |
| SCHEMBL18308715 | 0.82 | PTPN5 (0.42) | TSHRSMN1; SMN2NPC1RAB9AESR1 | |
| SCHEMBL3164981 | 0.82 | CYP1A2 (0.55) | HRH3CYP1A2CYP2A6CYP17A1CYP3A4 | |
| SCHEMBL30975085 | 0.81 | HRH3 (0.41) | HRH3CYP1A2CYP2A6CYP17A1CYP3A4 | |
| SCHEMBL18308706 | 0.81 | IDO1 (0.46) | HRH3CYP1A2CYP2A6ALDH1A1NPC1 | |
| SCHEMBL18308710 | 0.81 | IDO1 (0.46) | HRH3CYP1A2CYP2A6ALDH1A1NPC1 | |
| SCHEMBL30975090 | 0.81 | CYP11B1 (0.43) | HRH3CYP1A2CYP2A6CYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760935-B2 | Polymerizable compounds | MERCK PATENT GMBH (DE) | 2023-09-19 | — | — | US | disclosed |
| US-11739266-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760935-B2 | Polymerizable compounds | PARG, PHOSPHO1, PARN | HRH3 3365/4885CYP1A2 2742/4885CYP2A6 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.