Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26034663 | 0.90 | TRPV1 (0.40) | CYP2C9 | |
| SCHEMBL26034659 | 0.88 | CYP2C9 (0.42) | CYP2C9GAA | |
| SCHEMBL26037123 | 0.84 | CYP2C9 (0.47) | CYP2C9GAA | |
| SCHEMBL12918399 | 0.82 | CYP2C9 (0.46) | CYP2C9GAA | |
| SCHEMBL1020843 | 0.82 | CYP2C9 (0.56) | CYP2C9 | |
| SCHEMBL26034738 | 0.81 | CYP2C9 (0.44) | CYP2C9 | |
| SCHEMBL26037151 | 0.74 | CYP2C9 (0.48) | CYP2C9GAA | |
| SCHEMBL1017190 | 0.73 | CYP2C9 (0.58) | CYP2C9 | |
| SCHEMBL15424117 | 0.73 | CYP2C9 (0.57) | CYP2C9 | |
| SCHEMBL10287465 | 0.73 | CYP2C9 (0.47) | CYP2C9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265054-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265054-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | SHH, GLI1, SMO | CYP2C9 4725/4885GAA 4713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.