SCHEMBL260347

SCHEMBL260347

Clc1ccc(/C=C/c2ccc(Cl)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.74
CYP1A2 P05177 2/20 0.59
HSD17B10 Q99714 2/20 0.58
LMNA P02545 1/20 0.57
CYP2A6 P11509 1/20 0.57
ALOX5 P09917 1/20 0.56
PTGS1 P23219 1/20 0.56
PTGS2 P35354 1/20 0.56
NFE2L2 Q16236 1/20 0.56
FBP1 P09467 1/20 0.54
KDM4E B2RXH2 2/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPK1 P28482 1/20 0.52
MAPT P10636 1/20 0.52
MAOB P27338 1/20 0.50
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
DAO P14920 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1795502 1.00 AHR (0.74) AHRCYP1A2HSD17B10LMNACYP2A6
SCHEMBL20582895 1.00 AHR (0.74) AHRCYP1A2HSD17B10LMNACYP2A6
SCHEMBL10458457 1.00 AHR (0.74) AHRCYP1A2HSD17B10LMNACYP2A6
SCHEMBL9679426 1.00 AHR (0.74) AHRCYP1A2HSD17B10LMNACYP2A6
SCHEMBL699666 1.00 AHR (0.74) AHRCYP1A2HSD17B10LMNACYP2A6
SCHEMBL9679429 1.00 AHR (0.74) AHRCYP1A2HSD17B10LMNACYP2A6
SCHEMBL1335873 0.91 AHR (0.64) AHRCYP1A2HSD17B10LMNACYP2A6
SCHEMBL9681143 0.91 AHR (0.64) AHRCYP1A2HSD17B10LMNACYP2A6
SCHEMBL9681139 0.91 AHR (0.64) AHRCYP1A2HSD17B10LMNACYP2A6
SCHEMBL699519 0.88 AHR (0.61) AHRCYP1A2LMNANFE2L2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0396943-B1 Optical storage medium and storage process NIPPON TELEGRAPH & TELEPHONE (JP) 1995-07-05 EP claimed
US-5124944-A OPTICAL STORAGE MEDIUM AND STORAGE PROCESS NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-06-23 US claimed
CN-119462319-A Method for isomerizing trans-1, 2-diaryl ethylene into cis-1, 2-diaryl ethylene 西湖大学 2025-02-18 CN disclosed
US-12084538-B2 Method for producing polymer LG CHEM, LTD. (KR) 2024-09-10 US disclosed
CN-114031774-B High-strength super-toughness poly-astragalus-arylene sulfide and preparation method thereof 中鼎凯瑞科技成都有限公司 2024-04-02 CN disclosed
CN-114031774-A High-strength super-toughness polystilbene aryl sulfide ether and preparation method thereof 中鼎凯瑞科技成都有限公司 2022-02-11 CN disclosed
CN-112299937-B Efficient preparation method of symmetrical diarylethene compound 大连理工大学 2021-09-24 CN disclosed
CN-112299937-A Efficient preparation method of symmetrical diarylethene compound 大连理工大学 2021-02-02 CN disclosed
US-20200354487-A1 Method for Producing Polymer LG CHEM, LTD. (KR) 2020-11-12 US disclosed
EP-3640267-A1 PREPARATION METHOD FOR POLYMER LG Chem, Ltd. (KR) 2020-04-22 EP disclosed
US-9684254-B2 Diamine compound and electrophotographic photosensitive member KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-06-20 US disclosed
EP-0391204-A2 Process for preparing moulded articles of polymers with E-configurated stilbene moieties BAYER AG (DE) 1990-10-10 EP disclosed
EP-0116955-B1 COMPLEXES OF (1,2-DIPHENYL-ETHYLENE DIAMINE) PLATINUM (II) Degussa Aktiengesellschaft (DE) 1987-05-20 EP disclosed
US-4598091-A (1,2-diphenyl)-ethylenediamine)-platinum (II) complex compounds DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-07-01 US disclosed
US-4533505-A REACTION OF ETHYLENE IWITH ACID HALIDES IN THE PRESENCE OF A BASE AND A PALLADIUM CATALYST CIBA-GEIGY CORPORATION (US) 1985-08-06 US disclosed
EP-0062005-B1 PROCESS FOR THE MANUFACTURE OF STYRENE AND/OR STILBENE DERIVATIVES CIBA-GEIGY AG (CH) 1985-06-26 EP disclosed
EP-0116955-A2 Complexes of (1,2-diphenyl-ethylene diamine) platinum (II) Degussa Aktiengesellschaft (DE) 1984-08-29 EP disclosed
EP-0062005-A1 Process for the manufacture of styrene and/or stilbene derivatives CIBA-GEIGY AG (CH) 1982-10-06 EP disclosed
US-4293717-A Process for preparing aldehydes and diols BAYER AKTIENGESELLSCHAFT (DE) 1981-10-06 US disclosed
US-3972944-A BORON OXIDE, BORIC ACID OR BORATE AND VANADIUM OR MOLYBDENUM CONTAINING CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1976-08-03 US disclosed