Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 8/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063324 | 0.93 | GAA (0.76) | GAARECQLTP53LMNAMEN1 | |
| SCHEMBL3051333 | 0.89 | MAPT (0.54) | GAARECQLTP53LMNAMEN1 | |
| SCHEMBL15614698 | 0.88 | GAA (0.61) | GAARECQLTP53LMNAMEN1 | |
| SCHEMBL17249531 | 0.85 | GAA (0.66) | GAARECQLTP53LMNAMEN1 | |
| SCHEMBL17249530 | 0.85 | GAA (0.66) | GAARECQLTP53LMNAMEN1 | |
| SCHEMBL16941540 | 0.85 | GAA (0.53) | GAARECQLTP53LMNAMEN1 | |
| SCHEMBL30754768 | 0.84 | GAA (0.57) | GAARECQLTP53LMNAMEN1 | |
| SCHEMBL22542867 | 0.84 | GAA (0.57) | GAARECQLTP53LMNAMEN1 | |
| SCHEMBL21499877 | 0.82 | GAA (0.66) | GAARECQLTP53LMNAMEN1 | |
| SCHEMBL15614740 | 0.81 | MAPT (0.74) | GAARECQLTP53LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159248-A1 | RE-SENSITIZING MULTIDRUG-RESISTANT (MDR) GRAM-NEGATIVE BACTERIA TO COLISTIN USING IONOPHORES | THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) | 2023-08-24 | — | — | WO | disclosed |