Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TK2 | O00142 | 10/20 | 0.41 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24205274 | 0.87 | CYP2C9 (0.44) | CYP2C9KMT2AMAPTTK2TK1 | |
| SCHEMBL26035390 | 0.87 | CYP2C9 (0.40) | CYP2C9KMT2AMAPTTK2TK1 | |
| SCHEMBL26035308 | 0.86 | CYP2C9 (0.48) | CYP2C9KMT2AMAPTTK2TK1 | |
| SCHEMBL26035362 | 0.84 | CYP2C9 (0.46) | CYP2C9KMT2AMAPTTK2TK1 | |
| SCHEMBL24205211 | 0.84 | CYP2C9 (0.46) | CYP2C9KMT2AMAPTTK2TK1 | |
| SCHEMBL26034605 | 0.84 | CYP2C9 (0.46) | CYP2C9KMT2AMAPTTK2TK1 | |
| SCHEMBL24205291 | 0.81 | TLR8 (0.51) | CYP2C9KMT2AMAPTTK2TK1 | |
| SCHEMBL26037019 | 0.80 | TK2 (0.38) | CYP2C9KMT2AMAPTTK2TK1 | |
| SCHEMBL24205273 | 0.80 | CYP2C9 (0.44) | CYP2C9KMT2AMAPTTK2TK1 | |
| SCHEMBL24205272 | 0.80 | CYP2C9 (0.46) | CYP2C9KMT2AMAPTTK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6A, PDE6D | CYP2C9 1630/4885KMT2A 4011/4885MAPT 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.