SCHEMBL26037500

SCHEMBL26037500

C1=CC(c2nc(-c3ccc(-c4ccccc4)cc3)nc(-c3cc(-c4ccc5ccc6ccccc6c5c4)cc4oc5ccccc5c34)n2)=CCC1

nearest known ligand 0.31

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PLA2G2A P14555 1/20 0.30
PLA2G4A P47712 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24972754 0.94 KDM4E (0.33) KDM4EALDH1A1HSD17B10KMT2A
SCHEMBL24315496 0.93 KDM4E (0.31) KDM4EALDH1A1HSD17B10KMT2A
SCHEMBL25651689 0.92 TSHR (0.32) KDM4EMAPTTSHRHSD17B10MAPK1
SCHEMBL26066809 0.91 KDM4E (0.31) KDM4EALDH1A1MAPTHPGDALOX15
SCHEMBL24907863 0.91 KDM4E (0.32) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL25854957 0.91 TDP1 (0.30)
SCHEMBL25830758 0.89 TSHR (0.31) MAPTTSHRKMT2A
SCHEMBL24315437 0.89 KDM4E (0.34) KDM4EALDH1A1MAPTHPGDALOX15
SCHEMBL25829268 0.89 KDM4E (0.33) KDM4EALDH1A1HSD17B10KMT2A
SCHEMBL23820999 0.88 MAPT (0.38) KDM4EALDH1A1MAPTHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4235829-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-08-30 EP disclosed