Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23809472 | 0.88 | CYP19A1 (0.38) | CYP19A1NQO2ATMCA1CA2 | |
| SCHEMBL26581499 | 0.83 | CYP19A1 (0.45) | CYP19A1NQO2ATMCA1CA2 | |
| SCHEMBL23809174 | 0.71 | MCL1 (0.45) | ATMCA1CA2GPR35KDM4E | |
| SCHEMBL26581394 | 0.70 | CYP19A1 (0.44) | CYP19A1NQO2ATMNPSR1MAPT | |
| SCHEMBL19332237 | 0.69 | MAPT (0.39) | CYP19A1NQO2ATMCA1CA2 | |
| SCHEMBL23809515 | 0.69 | ATM (0.39) | ATMMAPTALDH1A1HPGD | |
| SCHEMBL23809479 | 0.66 | KMT2A (0.44) | ATMCA1CA2CA7CA9 | |
| SCHEMBL26048303 | 0.65 | CYP19A1 (0.41) | CYP19A1NQO2ATMNPSR1MAPT | |
| SCHEMBL23809532 | 0.64 | KMT2A (0.43) | ATMMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL23809471 | 0.64 | MAPT (0.36) | CYP19A1NQO2CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423435-B1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | UNIV VANDERBILT (US) | 2023-08-23 | — | — | EP | disclosed |