Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4994907 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2AMEN1ALDH1A1HDAC8 | |
| SCHEMBL13165140 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2KMT2AMEN1ALDH1A1HDAC8 | |
| SCHEMBL5898624 | 0.88 | KMT2A (0.57) | SMN1; SMN2KMT2AMEN1ALDH1A1HDAC8 | |
| SCHEMBL5898611 | 0.87 | KMT2A (0.56) | SMN1; SMN2KMT2AMEN1ALDH1A1HDAC8 | |
| SCHEMBL6242176 | 0.86 | KMT2A (0.66) | SMN1; SMN2KMT2AMEN1ALDH1A1HDAC8 | |
| SCHEMBL28629956 | 0.86 | KMT2A (0.66) | SMN1; SMN2KMT2AMEN1ALDH1A1HDAC8 | |
| SCHEMBL15722147 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AMEN1ALDH1A1HDAC8 | |
| SCHEMBL13990634 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL13359249 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL16238618 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2AMEN1ALDH1A1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223368-A1 | MACROCYCLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2023-08-09 | — | — | EP | disclosed |