SCHEMBL26040587

SCHEMBL26040587

Cc1ccc(S(=O)(=O)OCCc2ccc(C(C)O[Si](C)(C)C(C)(C)C)cn2)cc1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA9 Q16790 1/20 0.34
APLNR P35414 1/20 0.33
PSMD10 O75832 1/20 0.32
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2883636 0.75 CA1 (0.36) CA12CA1CA9APLNRPSMD10
SCHEMBL15284136 0.75 CA12 (0.38) CA12CA1CA9APLNRPSMD10
SCHEMBL27248448 0.75 CA12 (0.38) CA12CA1CA9APLNRPSMD10
SCHEMBL15284498 0.75 CA12 (0.38) CA12CA1CA9APLNRPSMD10
SCHEMBL30467054 0.75 ESR1 (0.33)
SCHEMBL30467049 0.75 ESR1 (0.33)
SCHEMBL20332538 0.75 ESR1 (0.33)
SCHEMBL932051 0.74 HTR2A (0.44) CA12CA1CA9PSMD10ALDH1A1
SCHEMBL30292889 0.73 HRH3 (0.44) CA12CA1CA9PSMD10MEN1
SCHEMBL4316004 0.73 HRH3 (0.44) CA12CA1CA9PSMD10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11731963-B2 Process for preparing 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]-methyl]-2,4-thiazolidinedione and salts thereof MINORYX THERAPEUTICS S.L. (ES) 2023-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731963-B2 Process for preparing 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]-methyl]-2,4-thiazolidinedione and salts thereof CYP3A5, CYP3A4, UGT1A4 CA12 4505/4885CA1 4691/4885CA9 3840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.