Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17304017 | 0.88 | PDE4B (0.44) | DPP4HDAC1HDAC2GPR119PDE4B | |
| SCHEMBL1012726 | 0.85 | MAPT (0.46) | DPP4GPR119PDE4BMAPTNPC1 | |
| SCHEMBL17304222 | 0.85 | SCN9A (0.42) | DPP4USP30PDE4BMAPTALDH1A1 | |
| SCHEMBL17303726 | 0.83 | KDM4E (0.38) | DPP4HDAC1HDAC2PDE4BMAPT | |
| SCHEMBL17879568 | 0.80 | DPP4 (0.35) | DPP4GPR119MAPTNPC1ALDH1A1 | |
| SCHEMBL17304050 | 0.79 | MAPT (0.47) | DPP4GPR119PDE4BMAPTNPC1 | |
| SCHEMBL17303760 | 0.77 | PDE4B (0.46) | GPR119PDE4BPIK3CA | |
| SCHEMBL28007082 | 0.75 | DPP4 (0.45) | DPP4GPR119PDE4BMAPTNPC1 | |
| SCHEMBL17304130 | 0.74 | PDE4B (0.54) | GPR119PDE4BMAPTKDM4ETHRB | |
| SCHEMBL17304040 | 0.74 | MAPT (0.43) | DPP4GPR119PDE4BMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150592-B1 | ALK KINASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | SHANGHAI EMERALD WELLCARES PHARMACEUTICAL CO LTD (CN) | 2023-08-30 | — | — | EP | disclosed |