SCHEMBL26045249

SCHEMBL26045249

C=C(C)C(=O)Oc1ccc(-c2ccc(-c3ccc(C)c(F)c3)c(F)c2)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 5/20 0.47
AKR1C2 P52895 5/20 0.47
AKR1B10 O60218 2/20 0.45
AKR1C4 P17516 2/20 0.45
AKR1C1 Q04828 2/20 0.45
ELANE P08246 1/20 0.38
PDE3B Q13370 1/20 0.38
PDE3A Q14432 1/20 0.38
ACACB O00763 2/20 0.36
ACACA Q13085 2/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
APP P05067 1/20 0.36
CYP2C19 P33261 1/20 0.36
EPHX1 P07099 1/20 0.36
FFAR4 Q5NUL3 2/20 0.35
KMO O15229 2/20 0.34
SLC6A3 Q01959 1/20 0.34
FFAR1 O14842 1/20 0.34
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26044723 0.94 ELANE (0.42) AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1
SCHEMBL26144175 0.92 AKR1C3 (0.40) AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1
SCHEMBL26144162 0.92 AKR1C3 (0.40) AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1
SCHEMBL26044724 0.91 FFAR1 (0.39) AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1
SCHEMBL26144163 0.91 AKR1C3 (0.40) AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1
SCHEMBL26144150 0.90 AKR1C3 (0.38) AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1
SCHEMBL26144181 0.90 ELANE (0.40) AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1
SCHEMBL22881581 0.89 FFAR1 (0.41) AKR1C3AKR1C2ELANEACACBACACA
SCHEMBL26144183 0.89 ELANE (0.39) AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1
SCHEMBL26144168 0.88 FFAR1 (0.39) AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed