Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | IAPP | P10997 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5588615 | 0.88 | PRKCI (0.52) | PRKCITYRCNR1CNR2ALOX5 | |
| SCHEMBL5680757 | 0.86 | PRKCI (0.50) | PRKCITYRCNR1CNR2ALOX5 | |
| Hydrochloric Acid SCHEMBL21409697 | 0.86 | PRKCI (0.50) | PRKCITYRCNR1CNR2ALOX5 | |
| SCHEMBL9153690 | 0.86 | PRKCI (0.42) | PRKCITYRCNR1CNR2ALOX5 | |
| SCHEMBL5676407 | 0.82 | TYR (0.51) | PRKCITYRALOX5ELANECTSG | |
| SCHEMBL5676392 | 0.81 | TYR (0.59) | PRKCITYRALOX5KDM4EALDH1A1 | |
| SCHEMBL5677097 | 0.79 | PRKCI (0.45) | PRKCITYRCNR1CNR2ALOX5 | |
| SCHEMBL5195485 | 0.79 | TYR (0.52) | PRKCITYRCNR1CNR2ALOX5 | |
| SCHEMBL5445936 | 0.79 | PRKCI (0.60) | PRKCITYRCNR1CNR2ALOX5 | |
| SCHEMBL28593783 | 0.79 | PRKCI (0.37) | PRKCITYRALOX5ELANECTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746364-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-09-05 | — | — | US | disclosed |
| US-11739354-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-08-29 | — | — | US | disclosed |