Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 19/20 | 0.82 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.82 |
| ▸ | PIM1 | P11309 | 1/20 | 0.68 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.64 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858053 | 0.90 | MAP2K1 (1.00) | MAP2K1MAP2K2PIM1CAMK2BCYP3A4 | |
| SCHEMBL29482205 | 0.90 | MAP2K1 (1.00) | MAP2K1MAP2K2PIM1CAMK2BCYP3A4 | |
| SCHEMBL4861033 | 0.88 | MAP2K1 (0.82) | MAP2K1MAP2K2PIM1CAMK2BMAP2K5 | |
| SCHEMBL7051381 | 0.87 | MAP2K1 (0.96) | MAP2K1MAP2K2PIM1CAMK2BMAP2K5 | |
| SCHEMBL13667024 | 0.86 | MAP2K1 (0.84) | MAP2K1MAP2K2PIM1CAMK2BMAP2K5 | |
| SCHEMBL4863091 | 0.86 | MAP2K1 (0.80) | MAP2K1MAP2K2 | |
| SCHEMBL23851484 | 0.85 | MAP2K1 (0.78) | MAP2K1MAP2K2PIM1CAMK2BCYP3A4 | |
| SCHEMBL24195833 | 0.85 | MEN1 (0.73) | MAP2K1MAP2K2PIM1CAMK2BMAP2K5 | |
| SCHEMBL1563122 | 0.84 | MAP2K1 (0.82) | MAP2K1MAP2K2 | |
| SCHEMBL4861666 | 0.84 | MAP2K1 (1.00) | MAP2K1MAP2K2PIM1CAMK2BMAP2K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4233834-A2 | ARYL-ANILINE AND HETEROARYL-ANILINE COMPOUNDS FOR TREATMENT OF BIRTHMARKS | NFlection Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-4233865-A2 | ARYL-ANILINE AND HETEROARYL-ANILINE COMPOUNDS FOR TREATMENT OF SKIN CANCERS | NFlection Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |