Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26046804 | 0.83 | MEN1 (0.37) | KDM4ENPSR1HSD17B10MEN1KMT2A | |
| SCHEMBL24195652 | 0.82 | MAP2K1 (0.45) | MEN1KMT2AHDAC3HDAC1HDAC6 | |
| SCHEMBL24195906 | 0.81 | HDAC1 (0.39) | MEN1KMT2AHDAC3HDAC1HDAC6 | |
| SCHEMBL24195913 | 0.80 | HPGD (0.41) | KDM4ENPSR1HSD17B10MEN1KMT2A | |
| SCHEMBL24196016 | 0.75 | MAP2K1 (0.53) | KDM4EKDRMAP2K2MAP2K1 | |
| SCHEMBL24195780 | 0.75 | MAP2K1 (0.52) | HDAC3HDAC1HDAC6MAP2K2MAP2K1 | |
| SCHEMBL24195660 | 0.74 | MAP2K1 (0.48) | MAP2K2MAP2K1 | |
| SCHEMBL24196062 | 0.73 | MAP2K1 (0.42) | HDAC3HDAC1HDAC6MAP2K2MAP2K1 | |
| SCHEMBL24196057 | 0.73 | DHODH (0.35) | KDM4ENPSR1HSD17B10MEN1KMT2A | |
| SCHEMBL24196064 | 0.73 | MAP2K1 (0.33) | KDM4ENPSR1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4233865-A2 | ARYL-ANILINE AND HETEROARYL-ANILINE COMPOUNDS FOR TREATMENT OF SKIN CANCERS | NFlection Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |