Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 20/20 | 0.55 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.40 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24407608 | 0.87 | MAP2K1 (0.63) | MAP2K1MAP2K2MAP2K5 | |
| SCHEMBL23853915 | 0.85 | MAP2K1 (0.54) | MAP2K1MAP2K2 | |
| SCHEMBL28645657 | 0.85 | MAP2K1 (0.76) | MAP2K1MAP2K2MAP2K5 | |
| SCHEMBL31096355 | 0.85 | MAP2K1 (0.76) | MAP2K1MAP2K2MAP2K5 | |
| SCHEMBL24407570 | 0.85 | MAP2K1 (0.76) | MAP2K1MAP2K2MAP2K5 | |
| SCHEMBL31096371 | 0.85 | MAP2K1 (0.76) | MAP2K1MAP2K2MAP2K5 | |
| SCHEMBL24407510 | 0.85 | MAP2K1 (0.76) | MAP2K1MAP2K2MAP2K5 | |
| SCHEMBL31096306 | 0.81 | MAP2K1 (0.55) | MAP2K1MAP2K2 | |
| SCHEMBL24407546 | 0.81 | MAP2K1 (0.53) | MAP2K1MAP2K2 | |
| SCHEMBL23854231 | 0.81 | MAP2K1 (0.55) | MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4233865-A2 | ARYL-ANILINE AND HETEROARYL-ANILINE COMPOUNDS FOR TREATMENT OF SKIN CANCERS | NFlection Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |