Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.35 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28995580 | 1.00 | CYP2C9 (0.49) | CYP2C9NPSR1GLO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2601721 | 1.00 | CYP2C9 (0.49) | CYP2C9NPSR1GLO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5902803 | 0.85 | CYP2C9 (0.51) | CYP2C9NPSR1GLO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4099808 | 0.85 | CYP2C9 (0.51) | CYP2C9NPSR1GLO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4099809 | 0.85 | CYP2C9 (0.51) | CYP2C9NPSR1GLO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3230226 | 0.85 | CYP2C9 (0.58) | CYP2C9NPSR1GLO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2819752 | 0.82 | CYP2C9 (0.49) | CYP2C9NPSR1GLO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2819750 | 0.82 | CYP2C9 (0.49) | CYP2C9NPSR1GLO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22548601 | 0.82 | CYP2C9 (0.49) | CYP2C9NPSR1GLO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18936298 | 0.82 | CYP2C9 (0.49) | CYP2C9NPSR1GLO1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271934-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED PYRAZOLES | ADAMA MAKHTESHIM LTD. (IL) | 2023-08-31 | — | — | US | disclosed |
| US-20230271934-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED PYRAZOLES | ADAMA MAKHTESHIM LTD. (IL) | 2023-08-31 | — | — | US | disclosed |
| US-20230271934-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED PYRAZOLES | ADAMA MAKHTESHIM LTD. (IL) | 2023-08-31 | — | — | US | disclosed |
| EP-4204402-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED PYRAZOLES | Adama Makhteshim Ltd. (IL) | 2023-07-05 | — | — | EP | disclosed |
| CN-116056700-A | Process for the preparation of substituted pyrazoles | 阿达玛马克西姆有限公司 | 2023-05-02 | — | — | CN | disclosed |
| WO-2022043877-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED PYRAZOLES | ADAMA MAKHTESHIM LTD. (IL) | 2022-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271934-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED PYRAZOLES | CYP4F3, CYP4B1, CYP3A4 | CYP2C9 15/4885NPSR1 1793/4885GLO1 2437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.