SCHEMBL26048165

SCHEMBL26048165

NCc1ccc(Br)c(F)c1C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.31
KCNH2 Q12809 2/20 0.31
KDM1B Q8NB78 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6120394 0.82
SCHEMBL2297847 0.81 SOS1 (0.30)
SCHEMBL855788 0.77 KDM1A (0.44) KDM1AKCNH2KDM1B
SCHEMBL31226403 0.74 TAAR1 (0.41)
SCHEMBL10215365 0.74 KDM1A (0.33) KDM1AKCNH2KDM1B
SCHEMBL16652774 0.73 KDM1A (0.31) KDM1AKCNH2KDM1B
SCHEMBL29396883 0.73 KDM1A (0.31) KDM1AKCNH2KDM1B
SCHEMBL22659331 0.72 KDM1A (0.32) KDM1AKCNH2KDM1B
SCHEMBL2298157 0.71 SOS1 (0.33)
Hydrochloric Acid SCHEMBL25230650 0.71 KDM1A (0.32) KDM1AKCNH2KDM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3793994-B1 INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE BIOGEN MA INC (US) 2023-08-23 EP disclosed