Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28588513 | 0.83 | PSMB5 (0.42) | TSHR | |
| SCHEMBL6836726 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1HPGDTSHRHDAC3 | |
| SCHEMBL10058464 | 0.80 | AKT1 (0.39) | ESR1ESR2TYRKDM4EMAPK1 | |
| SCHEMBL6835901 | 0.79 | KDM4E (0.35) | KDM4EALDH1A1HPGDTDP1TSHR | |
| SCHEMBL14192255 | 0.76 | TSHR (0.42) | KDM4EALDH1A1HPGDTSHRALDH2 | |
| SCHEMBL16283615 | 0.76 | PTGS1 (0.41) | TYRALDH1A1MAOAHSD17B10MAPT | |
| SCHEMBL28426229 | 0.74 | PTPN1 (0.50) | ESR1ESR2TYRKDM4EGAA | |
| SCHEMBL5539003 | 0.73 | ESR1 (0.44) | ESR1ESR2CNR2KDM4EMAPK1 | |
| SCHEMBL834241 | 0.72 | ALDH2 (0.37) | KDM4EALDH1A1HPGDL3MBTL1TSHR | |
| SCHEMBL10158247 | 0.70 | ESR1 (0.42) | ESR1ESR2CNR2KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158719-B2 | Benzoxazine-formulations with reduced outgassing behaviour | HENKEL AG & CO. KGAA (DE) | 2012-04-17 | — | — | US | disclosed |
| US-8158719-B2 | Benzoxazine-formulations with reduced outgassing behaviour | HENKEL AG & CO. KGAA (DE) | 2012-04-17 | — | — | US | disclosed |
| US-20100099818-A1 | BENZOXAZINE-FORMULATIONS WITH REDUCED OUTGASSING BEHAVIOUR | HENKEL AG & CO. KGAA (DE) | 2010-04-22 | — | — | US | disclosed |
| US-20100099818-A1 | BENZOXAZINE-FORMULATIONS WITH REDUCED OUTGASSING BEHAVIOUR | HENKEL AG & CO. KGAA (DE) | 2010-04-22 | — | — | US | disclosed |
| WO-2008151946-A1 | ADHESIVE COMPOSITIONS | HENKEL AG & CO. KGAA (DE) | 2008-12-18 | — | — | WO | disclosed |