SCHEMBL2604975

SCHEMBL2604975

CCCCn1c(Cc2cc(OC)c(OC)c(OC)c2)nc2c(N)ncnc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 14/20 1.00
HSP90AB1 P08238 14/20 1.00
ERBB2 P04626 6/20 1.00
ADORA2A P29274 1/20 0.53
ADORA2B P29275 1/20 0.53
ADORA1 P30542 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10149976 0.94 HSP90AA1 (0.89) HSP90AA1HSP90AB1ERBB2ADORA2AADORA2B
SCHEMBL1964163 0.93 HSP90AA1 (0.86) HSP90AA1HSP90AB1ERBB2ADORA2AADORA2B
SCHEMBL14044861 0.91 HSP90AA1 (0.83) HSP90AA1HSP90AB1ERBB2ADORA2AADORA2B
SCHEMBL4321160 0.86 HSP90AA1 (0.75) HSP90AA1HSP90AB1ERBB2ADORA2AADORA2B
SCHEMBL4849461 0.86 HSP90AA1 (0.75) HSP90AA1HSP90AB1ERBB2ADORA2AADORA2B
SCHEMBL4848666 0.85 HSP90AA1 (0.74) HSP90AA1HSP90AB1ERBB2
SCHEMBL4850868 0.85 HSP90AA1 (0.74) HSP90AA1HSP90AB1ERBB2
SCHEMBL4855740 0.85 HSP90AA1 (0.74) HSP90AA1HSP90AB1ERBB2ADORA2AADORA2B
SCHEMBL14456059 0.84 HSP90AA1 (0.72) HSP90AA1HSP90AB1ERBB2ADORA2AADORA2B
SCHEMBL4852703 0.84 HSP90AA1 (0.79) HSP90AA1HSP90AB1ERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12356601-B2 Memory cell design TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2025-07-08 US claimed
CN-118374001-A High-strength low-temperature-resistant corrosion-resistant poly (siloxane-urethane) coating for ship and preparation method thereof 常州大学 2024-07-23 CN claimed
CN-116991036-A Fluorine-silicon modified polyurethane photoresist and preparation method thereof 常州大学 2023-11-03 CN claimed
EP-4268322-A1 APPARATUS FOR PROCESSING RADIO FREQUENCY SIGNALS Nokia Shanghai Bell Co., Ltd. (CN) 2023-11-01 EP claimed
US-11757014-B2 Memory chip structure having GAA transistors with different threshold voltages and work functions for improving performances in multiple applications TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2023-09-12 US claimed
CN-116671014-A Device for processing radio frequency signals 上海诺基亚贝尔股份有限公司 2023-08-29 CN claimed
US-20230262951-A1 MEMORY CELL DESIGN TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2023-08-17 US claimed
CN-116249340-A Memory device and structure 台湾积体电路制造股份有限公司 2023-06-09 CN claimed
US-20220231145-A1 MEMORY CHIP STRUCTURE HAVING GAA TRANSISTORS WITH DIFFERENT THRESHOLD VOLTAGES AND WORK FUNCTIONS FOR IMPROVING PERFORMANCES IN MULTIPLE APPLICATIONS TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2022-07-21 US claimed
WO-2022133819-A1 APPARATUS FOR PROCESSING RADIO FREQUENCY SIGNALS NOKIA SHANGHAI BELL CO., LTD. (CN) 2022-06-30 WO claimed
CN-122080761-A Ultra-smooth scale inhibition coating and preparation method thereof 2026-05-26 CN disclosed
US-12630663-B2 Aqueous polyurethane resin dispersion AGFA NV (BE) 2026-05-19 US disclosed
CN-122029246-A Method for producing a bonded structure, bonded structure and use of said bonded structure for producing a motor vehicle component SABIC环球技术有限责任公司 2026-05-12 CN disclosed
CN-122025831-A Secondary battery, method for manufacturing the same, and power consumption device 宁德时代新能源科技股份有限公司 2026-05-12 CN disclosed
EP-4731445-A1 MANUFACTURING METHOD OF DECORATED NATURAL LEATHER AGFA NV (BE) 2026-04-29 EP disclosed
US-20070197787-A1 Heat shock protein 90 inhibitors UNIVERSITY OF KANSAS 2007-08-23 US disclosed
US-20070178537-A1 Assays for detection of bioactive compounds that interact with heat shock protein 90 SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2007-08-02 US disclosed
WO-2007075572-A2 ORALLY ACTIVE PURINE-BASED INHIBITORS OF HEAT SHOCK PROTEIN 90 CONFORMA THERAPEUTICS CORPORATION (US) 2007-07-05 WO disclosed
US-20070129334-A1 Orally Active Purine-Based Inhibitors of Heat Shock Protein 90 CONFORMA THERAPEUTICS CORPORATION (US) 2007-06-07 US disclosed
US-20070129334-A1 Orally Active Purine-Based Inhibitors of Heat Shock Protein 90 CONFORMA THERAPEUTICS CORPORATION (US) 2007-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129334-A1 Orally Active Purine-Based Inhibitors of Heat Shock Protein 90 HSP90AB1, HSP90AA1, HSP90AB2P HSP90AA1 2/4885HSP90AB1 1/4885ERBB2 1609/4885
US-12630663-B2 Aqueous polyurethane resin dispersion PUF60, PCMT1, EED HSP90AA1 3254/4885HSP90AB1 3776/4885ERBB2 3598/4885
US-20070197787-A1 Heat shock protein 90 inhibitors HSP90AB2P, HSP90AB1, HSP90AA1 HSP90AA1 3/4885HSP90AB1 2/4885ERBB2 2735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.