Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26050345 | 0.98 | KDM4E (0.64) | KDM4ENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL26050343 | 0.97 | KDM4E (0.63) | KDM4ENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL15069086 | 0.93 | KDM4E (0.56) | KDM4ENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL4510937 | 0.90 | KDM4E (0.60) | KDM4ENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL25997252 | 0.85 | KDM4E (0.60) | KDM4ENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL22372349 | 0.84 | KDM4E (0.58) | KDM4ENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL22388888 | 0.83 | SLC16A3 (0.50) | KDM4ENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL21301263 | 0.83 | KDM4E (0.57) | KDM4ENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL15068889 | 0.83 | KDM4E (0.57) | KDM4ENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL15069051 | 0.82 | KDM4E (0.53) | KDM4ENPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12031178-B2 | Cyclooctatetraene containing dyes and compositions | ILLUMINA CAMBRIDGE LIMITED (GB) | 2024-07-09 | — | — | US | disclosed |
| US-20230265502-A1 | CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-08-24 | — | — | US | disclosed |