Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 14/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26050380 | 1.00 | PDK2 (0.56) | PDK2CYP1A2KDM4EMEN1LMNA | |
| SCHEMBL31464140 | 1.00 | PDK2 (0.56) | PDK2CYP1A2KDM4EMEN1LMNA | |
| SCHEMBL12362770 | 1.00 | PDK2 (0.56) | PDK2CYP1A2KDM4EMEN1LMNA | |
| SCHEMBL22151245 | 0.94 | PDK2 (0.51) | PDK2CYP1A2KDM4EMEN1LMNA | |
| SCHEMBL26050366 | 0.93 | PDK2 (0.50) | PDK2CYP1A2KDM4EMEN1LMNA | |
| SCHEMBL25815231 | 0.90 | PDK2 (0.49) | PDK2CYP1A2KDM4EMEN1LMNA | |
| SCHEMBL25858527 | 0.90 | PDK2 (0.49) | PDK2CYP1A2KDM4EMEN1LMNA | |
| SCHEMBL16858256 | 0.90 | PDK2 (0.49) | PDK2CYP1A2KDM4EMEN1LMNA | |
| SCHEMBL29897946 | 0.90 | PDK2 (0.59) | PDK2CYP1A2MEN1LMNAMAPT | |
| SCHEMBL28854438 | 0.90 | PDK2 (0.59) | PDK2CYP1A2MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271989-A1 | METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271989-A1 | METAL COMPLEXES | AP3M1, AP1M1, AP2M1 | PDK2 1385/4885CYP1A2 4158/4885KDM4E 3576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.