Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | SAT1 | P21673 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9744983 | 0.82 | ANPEP (0.33) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL8597187 | 0.78 | CYP2C19 (0.56) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL22793891 | 0.78 | CYP2C19 (0.55) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL903694 | 0.78 | ANPEP (0.47) | ANPEPERAP2 | |
| SCHEMBL21649314 | 0.77 | ANPEP (0.31) | ANPEPERAP2 | |
| SCHEMBL331540 | 0.74 | CYP2C19 (0.80) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL331498 | 0.74 | CYP2C19 (0.80) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL13893419 | 0.74 | CYP2C19 (0.80) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL19620508 | 0.74 | CYP2C19 (0.80) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL7089751 | 0.74 | CYP2C19 (0.80) | CYP2C19CYP1A2KDM1AMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164237-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-08-31 | — | — | WO | disclosed |