Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 13/20 | 0.54 |
| ▸ | PAK1 | Q13153 | 3/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | PAK4 | O96013 | 2/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | PAK3 | O75914 | 1/20 | 0.44 |
| ▸ | PAK2 | Q13177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25370665 | 0.87 | PAK1 (0.49) | IGF1RPAK1AURKAPAK4SRC | |
| SCHEMBL30566830 | 0.87 | PAK1 (0.49) | IGF1RPAK1AURKAPAK4SRC | |
| SCHEMBL26049061 | 0.83 | PAK1 (0.57) | IGF1RPAK1AURKAPAK4PAK3 | |
| SCHEMBL25370237 | 0.81 | PAK1 (0.54) | IGF1RPAK1AURKAPAK4SRC | |
| SCHEMBL26049032 | 0.81 | PAK1 (0.58) | IGF1RPAK1AURKAPAK4PAK3 | |
| SCHEMBL30558788 | 0.79 | IGF1R (0.54) | IGF1RPAK1PAK4SRC | |
| SCHEMBL25368424 | 0.79 | IGF1R (0.54) | IGF1RPAK1PAK4SRC | |
| SCHEMBL25403360 | 0.77 | PAK1 (0.46) | IGF1RPAK1AURKAPAK4SRC | |
| SCHEMBL30503921 | 0.77 | PAK1 (0.46) | IGF1RPAK1AURKAPAK4SRC | |
| SCHEMBL24065231 | 0.77 | PAK1 (0.48) | IGF1RPAK1PAK4SRCPAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164611-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2023-08-31 | — | — | WO | disclosed |