Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.47 |
| ▸ | CETP | P11597 | 2/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25370259 | 0.89 | EPHX2 (0.61) | EPHX2MAPK14ROCK1ROCK2CETP | |
| SCHEMBL26050884 | 0.88 | EPHX2 (0.44) | EPHX2MAPK14CACNA1GCACNA1HCACNA1I | |
| SCHEMBL26052204 | 0.87 | EPHX2 (0.43) | EPHX2MAPK14MAPK1 | |
| SCHEMBL26051452 | 0.86 | EPHX2 (0.49) | EPHX2MAPK14ROCK1ROCK2CETP | |
| SCHEMBL26050637 | 0.83 | EPHX2 (0.49) | EPHX2MAPK14MAPK1 | |
| SCHEMBL25369344 | 0.82 | MAPK14 (0.54) | EPHX2MAPK14ROCK1ROCK2CETP | |
| SCHEMBL26050881 | 0.81 | EPHX2 (0.45) | EPHX2MAPK1EPHX1 | |
| SCHEMBL25370459 | 0.81 | MAPK14 (0.53) | EPHX2MAPK14ROCK1ROCK2CETP | |
| SCHEMBL25371803 | 0.81 | MAPK14 (0.53) | EPHX2MAPK14ROCK1ROCK2CETP | |
| SCHEMBL30229676 | 0.81 | MAPK14 (0.53) | EPHX2MAPK14ROCK1ROCK2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158584-A1 | NEW BICYCLOPENTANE DERIVATIVES | ICAGEN, LLC (US) | 2023-08-24 | — | — | WO | disclosed |