SCHEMBL26050772 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	HDAC6	Q9UBN7	13/20	0.45

▸	HDAC1	Q13547	4/20	0.38

▸	HDAC3	O15379	3/20	0.38

▸	HDAC2	Q92769	3/20	0.38

▸	HDAC10	Q969S8	2/20	0.38

▸	HDAC8	Q9BY41	2/20	0.38

▸	HDAC4	P56524	1/20	0.38

▸	HDAC7	Q8WUI4	1/20	0.38

▸	HDAC11	Q96DB2	1/20	0.38

▸	HDAC9	Q9UKV0	1/20	0.38

▸	HDAC5	Q9UQL6	1/20	0.38

▸	KDM2B	Q8NHM5	1/20	0.36

▸	HRH3	Q9Y5N1	2/20	0.35

▸	ENPP2	Q13822	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26050856	0.97	HDAC6 (0.49)	HDAC6HDAC1HDAC3HDAC2HDAC10
SCHEMBL26050771	0.95	HDAC6 (0.44)	HDAC6HDAC1HDAC3HDAC2HDAC10
SCHEMBL26056160	0.89	HDAC6 (0.45)	HDAC6HDAC1HDAC3HDAC2HDAC10
SCHEMBL26050864	0.88	HDAC6 (0.39)	HDAC6HDAC1HDAC3HDAC2HDAC10
SCHEMBL26051877	0.86	HDAC6 (0.42)	HDAC6HDAC1HDAC3HDAC2HDAC10
SCHEMBL26051875	0.86	HDAC6 (0.37)	HDAC6HDAC1HDAC3HDAC2HDAC10
SCHEMBL26051876	0.85	HDAC6 (0.37)	HDAC6HDAC1HDAC3HDAC2HDAC8
SCHEMBL26050917	0.85	HDAC6 (0.41)	HDAC6HDAC1HDAC3HDAC2HDAC10
SCHEMBL26050918	0.85	HDAC6 (0.41)	HDAC6HDAC1HDAC3HDAC2HDAC10
SCHEMBL26050852	0.85	HDAC6 (0.41)	HDAC6HDAC1HDAC3HDAC2HDAC10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023150203-A1	HDAC6 INHIBITORS AND USES THEREOF	EIKONIZO THERAPEUTICS, INC. (US)	2023-08-10	—	—	WO	disclosed