Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30541841 | 1.00 | AAK1 (0.39) | AAK1TRPA1TSHRLMNAKMT2A | |
| SCHEMBL26051336 | 0.86 | AAK1 (0.40) | AAK1TRPA1TSHRLMNAKMT2A | |
| SCHEMBL30541871 | 0.86 | AAK1 (0.40) | AAK1TRPA1TSHRLMNAKMT2A | |
| SCHEMBL17041209 | 0.86 | AAK1 (0.40) | AAK1TRPA1TSHRKMT2AMEN1 | |
| SCHEMBL17040888 | 0.86 | AAK1 (0.40) | AAK1TRPA1TSHRKMT2AMEN1 | |
| SCHEMBL17040765 | 0.86 | AAK1 (0.40) | AAK1TRPA1TSHRKMT2AMEN1 | |
| SCHEMBL18854490 | 0.84 | AAK1 (0.41) | AAK1KMT2AMEN1CTSSCTSK | |
| SCHEMBL30541840 | 0.84 | AAK1 (0.39) | AAK1TRPA1TSHRKMT2AMEN1 | |
| SCHEMBL26051971 | 0.84 | AAK1 (0.39) | AAK1TRPA1TSHRKMT2AMEN1 | |
| SCHEMBL30541845 | 0.83 | AAK1 (0.40) | AAK1TRPA1TSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793994-B1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | BIOGEN MA INC (US) | 2023-08-23 | — | — | EP | disclosed |