Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26051086 | 0.90 | HDAC6 (0.50) | HDAC6HDAC3HDAC1ADRA1AHDAC8 | |
| SCHEMBL26051040 | 0.90 | HDAC6 (0.54) | HDAC6HDAC3HDAC1HDAC2ADRA1A | |
| SCHEMBL26051087 | 0.89 | HDAC6 (0.51) | HDAC6ADRA1AHDAC8 | |
| SCHEMBL26051170 | 0.89 | HDAC6 (0.47) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL26051720 | 0.88 | HDAC6 (0.45) | HDAC6HDAC3HDAC1HDAC2ADRA1A | |
| SCHEMBL10224172 | 0.88 | HDAC6 (0.58) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL26050849 | 0.88 | HDAC6 (0.61) | HDAC6 | |
| SCHEMBL26051708 | 0.87 | HDAC6 (0.45) | HDAC6HDAC3HDAC1HDAC2ADRA1A | |
| SCHEMBL25348104 | 0.87 | HDAC6 (0.46) | HDAC6HDAC3HDAC1HDAC2ADRA1A | |
| SCHEMBL26050922 | 0.86 | HDAC6 (0.57) | HDAC6HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150203-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |