Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26050849 | 0.88 | HDAC6 (0.61) | HDAC6HRH3 | |
| SCHEMBL10224172 | 0.88 | HDAC6 (0.58) | HDAC6HRH3HDAC3HDAC1HDAC2 | |
| SCHEMBL26051085 | 0.87 | HDAC6 (0.52) | HDAC6HRH3 | |
| SCHEMBL26050922 | 0.87 | HDAC6 (0.57) | HDAC6HRH3HDAC3HDAC1HDAC2 | |
| SCHEMBL26051040 | 0.85 | HDAC6 (0.54) | HDAC6HRH3HDAC3HDAC1HDAC2 | |
| SCHEMBL26051169 | 0.83 | HDAC6 (0.53) | HDAC6HRH3 | |
| SCHEMBL26051087 | 0.82 | HDAC6 (0.51) | HDAC6HRH3 | |
| SCHEMBL26062657 | 0.82 | HDAC6 (0.52) | HDAC6HRH3HDAC3HDAC1HDAC2 | |
| SCHEMBL26051096 | 0.82 | HDAC6 (0.49) | HDAC6HRH3HDAC3HDAC1HDAC2 | |
| SCHEMBL26051086 | 0.81 | HDAC6 (0.50) | HDAC6HRH3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150203-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |