Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 6/20 | 0.56 |
| ▸ | PAK4 | O96013 | 5/20 | 0.56 |
| ▸ | AURKA | O14965 | 2/20 | 0.56 |
| ▸ | IGF1R | P08069 | 8/20 | 0.53 |
| ▸ | PAK3 | O75914 | 1/20 | 0.50 |
| ▸ | PAK2 | Q13177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26049032 | 0.86 | PAK1 (0.58) | PAK1PAK4AURKAIGF1RPAK3 | |
| SCHEMBL26049061 | 0.84 | PAK1 (0.57) | PAK1PAK4AURKAIGF1RPAK3 | |
| SCHEMBL25370237 | 0.81 | PAK1 (0.54) | PAK1PAK4AURKAIGF1RPAK3 | |
| SCHEMBL26576013 | 0.80 | PAK1 (0.63) | PAK1PAK4AURKAIGF1RPAK3 | |
| SCHEMBL26576010 | 0.77 | IGF1R (0.55) | PAK1PAK4AURKAIGF1RPAK3 | |
| SCHEMBL26050905 | 0.77 | PAK1 (0.53) | PAK1PAK4AURKAIGF1RPAK3 | |
| SCHEMBL30566830 | 0.77 | PAK1 (0.49) | PAK1PAK4AURKAIGF1RPAK3 | |
| SCHEMBL25370665 | 0.77 | PAK1 (0.49) | PAK1PAK4AURKAIGF1RPAK3 | |
| SCHEMBL30503948 | 0.76 | PAK1 (0.54) | PAK1PAK4AURKAIGF1RPAK3 | |
| SCHEMBL26271936 | 0.76 | PAK1 (0.54) | PAK1PAK4AURKAIGF1RPAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023163712-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023164611-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2023-08-31 | — | — | WO | disclosed |