SCHEMBL26053369

SCHEMBL26053369

c1ccc(-c2ccc(N(c3ccc4c(ccc5ccccc54)c3)c3cc4c5ccccc5ccc4c4ccccc34)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 5/20 0.41
ALDH1A1 P00352 5/20 0.39
HSD17B10 Q99714 3/20 0.39
CYP1B1 Q16678 3/20 0.39
HIF1A Q16665 1/20 0.39
TSHR P16473 2/20 0.35
CYP2A6 P11509 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 3/20 0.35
HPGD P15428 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 1/20 0.35
MPI P34949 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP1A2 P05177 4/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
SOS1 Q07889 1/20 0.34
CYP1A1 P04798 2/20 0.33
ERBB2 P04626 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26053253 0.96 HPRT1 (0.40) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL9971789 0.95 HPRT1 (0.45) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL26053270 0.95 HPRT1 (0.45) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL26053368 0.94 HPRT1 (0.41) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL26053248 0.94 HPRT1 (0.44) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL26053365 0.94 HPRT1 (0.44) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL9971924 0.92 HPRT1 (0.45) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL9971925 0.92 HPRT1 (0.45) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL26053826 0.92 HPRT1 (0.39) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL26053748 0.92 HPRT1 (0.39) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4235829-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-08-30 EP disclosed