Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 9/20 | 0.41 |
| ▸ | GART | P22102 | 1/20 | 0.41 |
| ▸ | ATIC | P31939 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | SLC19A1 | P41440 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15040289 | 0.91 | TYMS (0.59) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL434591 | 0.90 | TYMS (0.76) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL13658559 | 0.90 | TYMS (0.76) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL29853494 | 0.90 | TYMS (0.76) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL20247992 | 0.89 | TYMS (0.57) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL14947039 | 0.86 | TYMS (0.67) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL20386936 | 0.83 | TYMS (0.61) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL14264584 | 0.83 | TYMS (0.67) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL22302454 | 0.82 | AKR1B1 (0.57) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL17321175 | 0.82 | AKR1B1 (0.57) | TYMSKDM4EMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3151919-B1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | UNIV GEORGIA STATE RES FOUND (US) | 2023-08-30 | — | — | EP | disclosed |