SCHEMBL26060077

SCHEMBL26060077

CC1(C)c2ccccc2-c2c(N(c3ccc(-c4cccc5ccccc45)cc3)c3ccc4ccc5c6ccccc6ccc5c4c3)cccc21

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.32
ACMSD Q8TDX5 1/20 0.32
ENPP3 O14638 1/20 0.32
ENPP1 P22413 1/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CHRNB4 P30926 2/20 0.32
CHRNA3 P32297 2/20 0.32
CHRNA7 P36544 1/20 0.32
PPARG P37231 7/20 0.31
PPARA Q07869 7/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
CHRNA1 P02708 1/20 0.31
CHRNG P07510 1/20 0.31
CHRNB1 P11230 1/20 0.31
CHRNB2 P17787 1/20 0.31
SLC6A2 P23975 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26060547 0.96 MCL1 (0.32) MCL1ACMSDENPP3ENPP1CA12
SCHEMBL26060189 0.95 CA12 (0.36) ENPP3ENPP1CA12CA1CA2
SCHEMBL26060067 0.94 HPRT1 (0.31) MCL1ACMSDHPRT1PDK2
SCHEMBL26059562 0.94 HPRT1 (0.33) MCL1ACMSDENPP3ENPP1CA12
SCHEMBL26060943 0.93 HPRT1 (0.33) ENPP3ENPP1CA12CA1CA2
SCHEMBL26060662 0.93 CA12 (0.36) ENPP3ENPP1CA12CA1CA2
SCHEMBL26059455 0.93 HPRT1 (0.33) ENPP3ENPP1CA12CA1CA2
SCHEMBL24078502 0.93 HPRT1 (0.30) HPRT1
SCHEMBL26060081 0.93 CHRNA1 (0.34) MCL1ACMSDCHRNB4CHRNA3CHRNA1
SCHEMBL26060069 0.92 HPRT1 (0.33) HPRT1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4235829-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-08-30 EP disclosed