Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 19/20 | 0.54 |
| ▸ | KDR | P35968 | 12/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405191 | 0.86 | RET (0.57) | RETKDRSRCABL1 | |
| SCHEMBL20552974 | 0.86 | RET (0.57) | RETKDRSRCABL1 | |
| Trifluoroacetic Acid SCHEMBL21528139 | 0.81 | RET (0.54) | RETKDRSRCABL1 | |
| Trifluoroacetic Acid SCHEMBL29669791 | 0.81 | RET (0.54) | RETKDRSRCABL1 | |
| SCHEMBL21528193 | 0.80 | RET (0.63) | RETKDRSRCABL1 | |
| SCHEMBL30404443 | 0.80 | RET (0.63) | RETKDRSRCABL1 | |
| SCHEMBL21528141 | 0.80 | RET (0.53) | RETKDR | |
| Trifluoroacetic Acid SCHEMBL29669754 | 0.76 | RET (0.55) | RETKDRSRCABL1 | |
| Trifluoroacetic Acid SCHEMBL21528199 | 0.76 | RET (0.55) | RETKDRSRCABL1 | |
| SCHEMBL20552797 | 0.76 | PIK3CD (0.64) | RETKDRSRCABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234031-A2 | C40-, C28-, AND C-32-LINKED RAPAMYCIN ANALOGS AS MTOR INHIBITORS | Revolution Medicines, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |