Sugi Predict

Sugi Predict / Compounds / SCHEMBL2606147

SCHEMBL2606147

SCHEMBL2606147

O=C1c2ccccc2C(c2cc(-c3cccc(-c4ccccc4)c3)cc(-c3cccc(-c4ccccc4)c3)c2)(c2cc(-c3cccc(-c4ccccc4)c3)cc(-c3cccc(-c4ccccc4)c3)c2)c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.43
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ LMNA P02545 2/20 0.43
▸ NPC1 O15118 2/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ APAF1 O14727 1/20 0.43
▸ THRB P10828 1/20 0.43
▸ XBP1 P17861 1/20 0.43
▸ PTBP1 P26599 1/20 0.43
▸ HTT P42858 1/20 0.43
▸ GALK1 P51570 1/20 0.43
▸ BLM P54132 1/20 0.43
▸ SMAD3 P84022 1/20 0.43
▸ ATM Q13315 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ EDNRB P24530 1/20 0.39
▸ EDNRA P25101 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12166439 0.91 MAPT (0.37) MAPTSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL12166433 0.90 MAPT (0.36) MAPTSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL12166434 0.90 MAPT (0.36) MAPTSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL12166435 0.88 MAPT (0.35) MAPTSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL12166429 0.88 MAPT (0.37) MAPTSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL12166441 0.87 MAPT (0.36) MAPTSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL12166446 0.87 MAPT (0.36) MAPTSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL12166443 0.86 MAPT (0.36) MAPTSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL1167923 0.86 MEN1 (0.48) MAPTSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL19020415 0.86 MEN1 (0.48) MAPTSMN1; SMN2MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8361638-B2 Fluorine derivatives for organic electroluminescence devices MERCK PATENT GMBH (DE) 2013-01-29 — — US disclosed
US-8361638-B2 Fluorine derivatives for organic electroluminescence devices MERCK PATENT GMBH (DE) 2013-01-29 — — US disclosed
EP-2260023-B1 FLUORENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2012-04-25 — — EP disclosed
US-20110037027-A1 FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2011-02-17 — — US disclosed
US-20110037027-A1 FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2011-02-17 — — US disclosed
WO-2009124627-A1 FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2009-10-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110037027-A1 FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES SLCO4C1, CTCF, AFF2 MAPT 302/4885SMN1; SMN2 3068/4885MEN1 428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.