Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 10/20 | 0.58 |
| ▸ | ABL1 | P00519 | 7/20 | 0.58 |
| ▸ | KDR | P35968 | 5/20 | 0.58 |
| ▸ | HCK | P08631 | 5/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.58 |
| ▸ | PRKDC | P78527 | 5/20 | 0.58 |
| ▸ | EGFR | P00533 | 4/20 | 0.58 |
| ▸ | MTOR | P42345 | 4/20 | 0.58 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.58 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.53 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.53 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.53 |
| ▸ | LCK | P06239 | 3/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
| ▸ | PLK4 | O00444 | 1/20 | 0.48 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14617265 | 0.93 | ABL1 (0.64) | SRCABL1KDRHCKPIK3CD | |
| SCHEMBL3684615 | 0.86 | JAK2 (0.56) | SRCABL1KDRHCKPIK3CD | |
| SCHEMBL19362386 | 0.84 | SRC (0.45) | SRCABL1KDRHCKPIK3CD | |
| SCHEMBL19362539 | 0.84 | SRC (0.45) | SRCABL1KDRHCKPIK3CD | |
| SCHEMBL19362459 | 0.84 | SRC (0.45) | SRCABL1KDRHCKPIK3CD | |
| SCHEMBL25678106 | 0.83 | JAK2 (0.53) | SRCABL1KDRHCKPIK3CD | |
| SCHEMBL25678092 | 0.82 | SRC (0.52) | SRCABL1KDRHCKPIK3CD | |
| SCHEMBL17962825 | 0.80 | RET (0.56) | SRCABL1KDRPIK3CDPIK3CA | |
| SCHEMBL17936188 | 0.79 | KCNH2 (0.56) | SRCABL1KDRPIK3CDPIK3CA | |
| SCHEMBL24251864 | 0.79 | SRC (0.64) | SRCABL1KDRHCKPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234031-A2 | C40-, C28-, AND C-32-LINKED RAPAMYCIN ANALOGS AS MTOR INHIBITORS | Revolution Medicines, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |