Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GLP1R | P43220 | 8/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25546667 | 0.94 | KMT2A (0.59) | KMT2AMEN1GLP1RCYP2D6CYP2C9 | |
| SCHEMBL21105478 | 0.94 | KMT2A (0.59) | KMT2AMEN1GLP1RCYP2D6CYP2C9 | |
| SCHEMBL21105932 | 0.94 | KMT2A (0.59) | KMT2AMEN1GLP1RCYP2D6CYP2C9 | |
| SCHEMBL22837635 | 0.94 | KMT2A (0.59) | KMT2AMEN1GLP1RCYP2D6CYP2C9 | |
| SCHEMBL24812863 | 0.90 | KMT2A (0.53) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25122775 | 0.88 | KMT2A (0.53) | KMT2AMEN1GLP1RCYP2D6CYP2C9 | |
| SCHEMBL25028591 | 0.88 | KMT2A (0.53) | KMT2AMEN1GLP1RCYP2D6CYP2C9 | |
| SCHEMBL22856474 | 0.88 | KMT2A (0.53) | KMT2AMEN1GLP1RCYP2D6CYP2C9 | |
| SCHEMBL24470294 | 0.88 | MEN1 (0.45) | KMT2AMEN1GLP1RSMN1; SMN2TSHR | |
| SCHEMBL26429195 | 0.88 | MEN1 (0.45) | KMT2AMEN1GLP1RTSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161875-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR PROSTATE SPECIFIC MEMBRANE ANTIGEN-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023161874-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR C-C CHEMOKINE RECEPTOR 2-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-31 | — | — | WO | disclosed |