Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HHAT | Q5VTY9 | 5/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24049370 | 0.92 | GRIN2C (0.50) | HHATGRIN2CTP53 | |
| SCHEMBL26065112 | 0.81 | GRIN2C (0.40) | GRIN2CTP53 | |
| SCHEMBL26065070 | 0.79 | GRIN2C (0.62) | GRIN2C | |
| SCHEMBL26065095 | 0.77 | TSHR (0.55) | HHATGRIN2C | |
| SCHEMBL24049085 | 0.73 | GRIN2C (0.48) | GRIN2CTP53 | |
| SCHEMBL24049372 | 0.72 | GRIN2C (0.75) | GRIN2C | |
| SCHEMBL24049366 | 0.71 | TSHR (0.61) | HHATGRIN2C | |
| SCHEMBL26065097 | 0.70 | GRIN2C (0.51) | GRIN2C | |
| SCHEMBL26065077 | 0.69 | HHAT (0.48) | HHATGRIN2C | |
| SCHEMBL26065099 | 0.69 | GRIN2C (0.46) | GRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355593-A1 | N-methyl-D-aspartic Acid Receptor Modulators | UNIV EMORY (US) | 2023-11-09 | — | — | US | disclosed |
| US-11738008-B2 | N-methyl-D-aspartic acid receptor modulators | EMORY UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230355593-A1 | N-methyl-D-aspartic Acid Receptor Modulators | GRIN1, GRIN2A, GRM1 | HHAT 944/4885GRIN2C 9/4885TP53 3107/4885 |
| US-11738008-B2 | N-methyl-D-aspartic acid receptor modulators | GRIN1, GRIN2A, GRM1 | HHAT 979/4885GRIN2C 8/4885TP53 3189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.