Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | IDH2 | P48735 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065509 | 0.88 | LRRK2 (0.32) | — | |
| SCHEMBL26065513 | 0.88 | TLR9 (0.31) | — | |
| SCHEMBL26066088 | 0.88 | IRAK4 (0.33) | PDE9A | |
| SCHEMBL26065529 | 0.87 | TLR9 (0.34) | — | |
| SCHEMBL26066092 | 0.87 | LRRK2 (0.33) | PDE9A | |
| SCHEMBL26066125 | 0.85 | — | — | |
| SCHEMBL26066127 | 0.85 | KCNH2 (0.32) | PDE9A | |
| SCHEMBL26065921 | 0.82 | PTPN11 (0.37) | — | |
| SCHEMBL26065407 | 0.81 | LRRK2 (0.31) | — | |
| SCHEMBL25372155 | 0.76 | PSEN1 (0.38) | PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |